Table 2

	OR	SD + PD	p
Age (years) Means ± standard deviation Gender (M/F)	58.65 ± 8.53	56.27 ± 10.75	0.426
Male	16 (34.0%)	31 (66.0%)	0.412
Female	1 (14.3%)	6 (85.7%)
Etiology HBV + HCV Alcohol + Idiopathic Type of tumor Single + Massive Diffuse + Multi-nodular PVTT Yes No Grade of PVTT Vp2 Vp3 Vp4 Child-Pugh Class A B + C Albumin (g/dL) ≥ 3.5 〈 3.5 Bilirubin (mg/dL) ≤ 1.2 〉 1.2 PT (INR) ≤ 1 〉 1 ALT (U/I) 〉 40 ≤ 40 AFP (ng/mL) ≥ 200 〈 200 Ascites Yes No Previous treatment Yes No	14 (31.8%) 3 (30.0%) 8 (25.0%) 9 (40.9%) 9 (22.5%) 8 (57.1%) 1 (16.7%) 2 (12.5%) 6 (33.3%) 10 (30.3%) 7 (33.3%) 5 (23.8%) 12 (36.4%) 8 (34.8%) 9 (29.0%) 1 (12.5%) 16 (34.8%) 7 (26.9%) 10 (35.7%) 7 (21.2%) 10 (47.6%) 3 (25.0%) 14 (33.3%) 10 (37.0%) 7 (25.9%)	30 (68.2%) 7 (70.0%) 24 (75.0%) 13 (59.1%) 31 (77.5%) 6 (42.9%) 5 (83.3%) 14 (87.5%) 12 (66.7%) 23 (69.7%) 14 (66.7%) 16 (76.2%) 21 (63.6%) 15 (65.2%) 22 (71.0%) 7 (87.5%) 30 (65.2%) 19 (73.1%) 18 (64.3%) 26 (78.8%) 11 (52.4%) 9 (75.0%) 28 (66.7%) 17 (63.0%) 20 (74.1%)	1.000 0.246 0.023 0.405 1.000 0.383 0.769 0.260 0.565 0.070 0.732 0.559

OR: Objective response; SD: Stable disease; PD: Progressive; HBV: Hepatitis B Virus; HCV: Hepatitis C Virus; PVTT: Portal Vein Tumor Thrombosis; Vp1: Invasion (or tumor thrombus in) distal to the second order branches of the portalvein, but not of the second order branches; Vp2: Invasion of (or tumor thrombus in) second order branches of the portal vein; Vp3: Invasionof (or tumor thrombus in) first order branches of the portal vein; Vp4: Invasion of (or tumor thrombus in) the main trunk of the portal veinand/or contra-lateral portal vein branch to the primarily involved lobe; PT: Prothrombin Time; INR: International Normalized Ratio; ALT: Alanine Transaminase: AFP: Alpha-fetoprotein; HAIC: Hepatic Arterial Infusion Chemotherapy; 5-FU: Fluorouracil

Table 2: Effect of Pre-treatment Variables on the Therapeutic Effect of HAIC in Patients with Advanced HCC according to the Results of Univariate Analysis.