Figure 1: FBXW7 expression level in human breast cancer and normal tissues. FBXW7 mRNA expression is assessed by Affymetrix microarray. FBXW7 expression is measured as log2 (probe intensities). In both dataset GSE10780 (dataset 11 in Table 1) (a) and GSE3844 (dataset 12 in Table 1) (b), FBXW7 mRNA expression level is significantly reduced in breast tumors in comparison to normal breast tissues.