Tissue |
No. of samples |
Cell type |
Luminal epithelial |
Basal |
SGLT1-postive stromal cells (%) ** |
Normal |
3 |
+ |
+ |
Stromal cells are negative |
BPH |
53 |
+ and - |
+++ |
62.4 ± 31.7 |
PIN |
9 |
++ |
++ |
NA |
PCa |
44 |
+++ |
NA |
++ to +++, 3.8 ± 5.4% |
*The semi-quantification was carried out by two individuals in a blinded manner using the same normal prostate tissue as a standard reference. The signal density of normal prostate epithelial cells is considered as “+”, and the signal density of the basal cells of BPH is considered as “+++”.
**SGLT1-positive cells and total stromal cells were counted from 3 random selected areas under 200x magnification, and the percentage of SGLT1-positive cells is calculated by the number of SGLT1-positive cells/total stromal cells. The values are presented as mean ± SD.
NA: not applicable |