MDM2 G2580T Genotype

Cases (n=136)

Control (n=136)

OR*(95% CI)

RR**

RD***

P value

TT(ref)

28

58

1.00

1.00

 

 

TG

78

62

2.60(1.49-4.57)

1.52(1.20-1.93)

23.16(10.3-36.0)

0.0009

GG

30

16

3.88(1.82-8.27)

1.94(1.27-2.96)

32.6(15.7-49.6)

0.0004

TG+GG

108

78

2.87(1.68-4.91)

1.61(1.29-2.01)

25.5(13.3-37.7)

0.0001

*OR- Odd ratio **RR- Risk ratio ***RD- Risk difference
Table 3: Risk of lung cancer associated with the MDM2 (-309T/G) genotypes.