Variables N ADAM33 IHC p ADAM33 p     Neg Pos   U M   ADAM33 IHC               Positive 39 - - - 29 10 0.0004 Negative 7 - - 0 7 Histologicaltype               IDC 38 0 38 <0.0001 25 11 0.0765 ILC 11 7 4 4 7 Neg: negative; pos: positive; U: unmethylated; M: methylated

Table 1: Clinicopathological features of the 49 patients with primary breast carcinomas according to ADAM33 gene methylation and immuhistochemical status.