S.No. Treatment SGPT (mg/dl) SGOT (mg/dl) ALP (mg/dl) GGPT (mg/dl) Total bilurubin mg/dl) ALB (mg/dl)
1 Vehicle control 49.99 ± 046 55.23 ± 1.04 06.13 ± 0.46 1.75 ± 0.11 0.61 ± 0.06 3.89 ± 0.23
2 DENA control 76.11 ±1.29** 75.24 ± 1.61*** 9.78 ± 0.56*** 2.67 ± 0.11*** 1.49 ± 0.65** 2.22 ± 0.09**
3 PGTG 72.23 ± 0.89*** 49.36 ± 0.85** 06.13 ± 0.37*** 1.59 ± 0.23 ** 0.45 ± 0.11*** 3.25 ± 0.14***
4 GTG 99.68 ± 1.25** 64.11 ± 1.33*** 06.46 ± 0.71*** 1.56 ± 0.56** 0.46 ± 0.19 *** 3.21 ± 0.09***
5 Gatifloxacin 40.51 ± 1.45** 39.26 ± 1.19*** 03.77 ± 0.64*** 0.72 ± 0.07 ** 0.25 ± 0.24** 3.71 ± 0.32***
Values are expressed as Mean ± SEM, (N=6); * Significance level: *p<0.05, **p<0.01 and ***p<0.001 as compared to DENA control.
Table 2: Effect of gatifloxacin on serum SGOT, SGPT, ALP, GGTP and TB of animals.