ID Sample Malignancy Breast Age Histological grade Stage Chemotherapy c-erbB2 ER PR 002 80% Left 64 Intermediate YPT4PN1M0 Yes - - - 004 100% Left 58 High T3N2aM0 Yes - - - 036 80% Left 56 High T2N1aM0 Yes - - - 005 80% Right 60 Low T2N1 M0 No low + + 014 100% Right 61 High T2N0 M0 No low + + 019 80% Left 54 Intermediate T4dN3 M0 Yes low + +

Table 1: Clinical and histopathological characteristics of breast cancer samples. The identification of tumor tissue from the removed sample was based on the histopathological examination, and all types of breast cancer were included. Samples were selected based on tumor content (minimally 80% tumor), as determined by microscopic pathological analysis. A sample of normal tissue was collected from each patient whenever possible. All cases represent ductal carcinoma in situ. c-erbB2: HER2/neu Epidermal Growth Factor Receptor; ER: Estrogen Receptor; PR: Progesterone Receptor.