DRUG % Apoptosis
Control 4
LM 0.5 nM 15.5
LM 1 nM 23
DR5 25 ng/ml 37.5
LM 0.5 nM + DR5 25ng/ml 44.5
LM 1 nM + DR5 25 ng/ml 51
Table 4: Effect of leptomycin, DR5 and their combination in varying concentrations on LNCAP cells. The LNCAP cells were plated at 10,000cells/ml in a 6 well plate and incubated for 24 hours. These were then treated with varying concentrations of leptomycin B, DR5 and their combinations and incubated for 24 hours. Images of cells were captured before and after incubation with drugs through light microscopy for calculating percentage apoptosis.