|
Control (n=6) |
Vehicle (n=6) |
Boldine (n=8) |
Coagulative necrosis |
5/6 (83,3%) |
6/6 (100%) |
5/8 (62,5%) |
Intratumoral hemorrhage |
6/6 (100%) |
6/6 (100%) |
6/8 (75%) |
Vascular proliferation |
6/6 (100%) |
6/6 (100%) |
7/8 (87,5%) |
Microabscess |
3/6 (50%) |
4/6 (66,6%) |
2/8 (25%) |
Lymphocytic infiltration |
6/6 (100%) |
6/6 (100%) |
6/6 (100%) |
Peripheral pseudopalisading |
3/6 (50%) |
3/6 (50%) |
5/8 (62,5%) |
The histological variables were regarded as present or absent. (n = number of
animals per group) |