Patient Number Agent (cytokine) Duration Of therapy (weeks) Tumor response Disease-free Period (months) Overall Survival Up to date (months) 1 GM-CSF 4 CR 22 48 2 GM-CSF 4 CR 44 44 3 GM-CSF IL-2 4 4 None CR - 12 - 36 4 GM-CSF 3 CR 12 31 5 GM-CSF IL-2 4 4 None None None None N/A 6 GM-CSF IL-2 4 4 None None None None N/A 7 GM-CSF IL-2 4 4 None None None None N/A 8 GM-CSF & IL-2 1 CR 36 36 9 GM-CSF 6 CR 6 N/A 10 GM-CSF 6 CR at injection sites, progression in lung metastases None N/A CR= complete tumor response N/A= not applicable as the patient received other therapy

Table 2: Intralesional Therapy & Summary of the Results.