Figure 5: Histopathological analysis of lung tissue. 5a-Normal mice - [Shows normal architecture of lungs with bronchioles, alveoli and interstitium]. 5b-lung of mice injected with B16F-10 cell line (cancer alone) - [Shows massive abnormal cell growth around the bronchioles and infiltration of melanoma in the interstitium of the lung, coarse granules of black melanin pigment are seen both inside the macrophages as well as outside them]. 5c-lung of treated group shows significant reduction in tumor mass and regeneration of alveolar passage with ciliated columnar epithelial cells and reduced metastatic foci in lungs showing luminal epithelial-like morphology with well differentiated secretory glands are seen and reduction in the coarse granules of black melanin pigment are also seen.