Figure S1: Effects of drug loaded tNPs in vitro on side population of CSCs. Both side population (SP) of CSCs and non-side population (non-SP) of bulk cancer cells were measured by FACS and Hoechst 33342 dye efflux in A549Luc cells after treatment in vitro with tNP-Dox, tNP-IMD-0354 or tNPDox- IMD-0354, and compared to control. Data are shown as mean ± SEM.