Figure 5: Colitis score values from SCID mice at day 25, 39 and 53 after transplantation showing colitis score for the TRANS, TRANS/AOM, AOM groups and a nontreated control group. Although some fluctuations in colitis score appeared for the TRANS and the TRANS/AOM groups during the period, these were not significant for any particular day or treatment (A). Mean crypt depth in sections from mid colon and rectum. Crypts in the TRANS and TRANS/AOM group were hyper-proliferative with a crypt depth more than two fold of crypts from a non-treated control group. No difference between TRANS and TRANS/AOM (B). Photographs showing similar degrees of inflammation in the TRANS and TRANS/AOM groups and the absence of inflammation in AOM treated mice (C). |