MTHFRC677T Controls, n=137 Gastric cancer, n=43 CRC, n=78 GC CRC  
P value P value  OR 95%CI
CC 78(56.9%) 24(55.8%) 32(41%)      
CT 53(38.7%) 17(39.5%) 38(48.7%) 0.908 0.060  
TT 6(4.4%) 2(4.7%) 8(10.3%) 0.925 0.034 3.25(1.044-10.118)
C 209(76.3%) 65(75.6%) 102(65.4%)      
T 65(23.7%) 21(24.4%) 54(34.6%) 0.900 0.015 1.702(1.106-2.621)
MTHFRA1298C Controls, n=78 GC, n=35 CRC, n=72      
AA 40(51.3%) 24(68.6%) 47(65.3%)      
AC 34(43.6%) 9(25.7%) 21(29.2%) 0.068  0.065  
CC 4(5.1%) 2(5.7%) 4(5.6%) 0.827  0.827  
A 114(73.1%) 57(81.4%) 115(79.9%)      
C 42(26.9%) 13(18.6%) 29(20.1%) 0.18 0.17  
Table 2: Genotypes distribution of MTHFR C677T polymorphism and MTHFR A1298C among gastrointestinal cancers and controls.