| |
|
MTHFR C677T |
|
|
|
MTHFR A1298C |
|
P *for interaction |
| CC |
CT |
TT |
P* for interaction |
AA |
AC |
CC |
| Colorectal cancer (n=74) |
|
|
|
|
|
|
|
|
| Stage |
|
|
|
|
|
|
|
|
| I |
0 |
2(50) |
2(50) |
0.43 |
2(100) |
0 |
0 |
0.53 |
| II |
3(30) |
7(70) |
0 |
5(45.5) |
4(36.4) |
2(18.2) |
| III |
14(41.2 |
18(52.9) |
2(5.9) |
20(62.5) |
9(28.1) |
3(9.4) |
| IV |
8(53.3) |
6(40) |
1(6.7) |
8(72.7) |
3(27.3) |
0 |
| Lymph node status |
|
|
|
|
|
|
| <4 nodes |
10(40) |
14(56) |
1(4) |
0.42 |
16(69.6) |
4(17.4) |
3(13) |
0.45 |
| ≥4 nodes |
6(54.5) |
4(36.4) |
1(9.1) |
5(55.6) |
4(44.4) |
0 |
| Differentiation |
|
|
|
|
|
|
|
|
| Moderately differentiated |
12(48) |
12(48) |
1(4) |
0.23** |
11(55) |
7(35) |
2(10) |
0.34 |
| Well differentiated |
14(33.3) |
25(59.5) |
3(7.1) |
27(67.5) |
10(25) |
3(7.5) |
| Histological type
ADK |
7(30.4) |
12(52.2) |
4(17.4) |
0.24 |
12(60) |
6(30) |
2(10) |
0.60 |
| ADK Luberkhunien |
13(46.4) |
14(50) |
1(3.6) |
|
12(52.2) |
9(39.1) |
2(8.7) |
|
| ADK infiltrant |
3(50) |
3(50) |
0 |
|
6(90) |
1(10) |
0 |
|
| Other type of ADK |
4(16.2) |
8(80) |
1(3.8) |
0.42 |
10(65) |
3(31.2) |
1(3.8) |
0.46 |
P*: For MTHFR C677T, CC as reference group and CT grouped with TT; for MTHFR A1298C AA as reference grouped with AC+CC
P**: For differentiation was calculated between moderately and well differentiated |
