Name of Antibody Apparent Titer (nM) Negative control NA RP215 chimera (with human IgG) 4.2 FY1 5.7 FY2 13.1 FY3 8.4 FY4 4.4 FY5 9.6 FY6 7.1

Table 1A: The estimates of dissociation constants of humanized RP215 and other different forms.