Immunoglobulin chain   Region   Number of Similarities   Percent Similarities  
    FR1   23/30   77%  
FR2 11/14   79%  
FR3 25/38   66%  
Heavy Chain   Subtotal   59/93   63%
  JH   10/11   91%  
  Subtotal   10/11   91%
CDR1   5/5   100%  
CDR2 10/11   91%  
CDR3 4/4   100%  
  Subtotal   19/20   95%
Total     88/124   71%  
  FR1 15/23   65%  
FR2 13/15   87%  
FR3 30/34   88%  
FR4 10/10   100%  
Light Chain   Subtotal   68/82   83%
  CDR1   17/17   100%  
CDR2 5/5   100%  
CDR3 9/9   100%  
  Subtotal   31/31   100%
Total     99/103   96%  
Heavy and Light Chain   Total 187/227   82%  
Table 2: Comparisons of amino acid sequences homology in the FR and CDR domains in the Fab region of hRP215and mRP215.