Sample ID Thalidomide [nM] Celecoxib [µM] Rapamycin [µM] Bevacizumab [mg/ml] Cetuximab [µg/ml]
HROG02 >40 68 1.0 >2.5 >20
HROG04 >40 48 1.0 >2.5 >20
HROG05 40 51 1.5 >2.5 >20
HROG06 >40 126 3.0 >2.5 >20
HROG07 >40 171 6.0 >2.5 >20
HROG10 >40 74 6.0 >2.5 >20
HROG13 >40 60 2.7 >2.5 >20
HROG15 >40 67 3.0 >2.5 >20
HROG17 0.62 58 0.4 >2.5 >20
HROG24 >40 68 0.9 >2.5 >20
HROG36 10.0 60 2.4 >2.5 >20
HROG38 >40 68 31.0 >2.5 >20
Calculated IC50 values (after three independent assessments in triplicates) for 144 hour incubation with the therapeutic agents are provided for all cell lines
Table 7b: Drug sensitivity for novel and targeted therapeutics (IC50 values).