| Variable |
Non-Metformin user |
Metformin user |
Overall |
P value |
| Number |
368 (90%) |
41 (10%) |
409 (100%) |
|
| Age(Mean±SD); Range |
68.3±10.3; 21-93 |
71.0±8.8; 45-85 |
68.5±10.2; 21-93 |
0.131 |
| Gender-Male |
157 (42.7%) |
15 (36.6%) |
172 (42.1%) |
0.455 |
| Race
White
Others |
340 (92.4%)
28 (7.6%) |
35 (85.4%)
6 (14.6%) |
375 (91.7%)
34 (8.3%) |
0.122 |
| Smoking
Current
Previous
Never |
157 (42.7%)
179 (48.6%)
32 (8.7%) |
12 (29.3%)
24 (58.5%)
5 (12.2%) |
169 (41.3%)
203 (49.6%)
37 (9%) |
0.243 |
| Surgery
Lobectomy
Pneumonectomy |
360 (97.8%)
8 (2.2%) |
41 (100%)
0 (0%) |
401 (98%)
8 (2.0%) |
0.688 |
| Histology
Adenocarcinoma
SqCC
Others |
224 (60.9%)
108 (29.3%)
36 (9.8%) |
20 (48.8%)
16 (39%)
5 (12.2%) |
244 (59.7%)
124 (30.3%)
41 (10%) |
0.323 |
| Pathologic stage
IA
IB |
231 (62.8%)
137 (37.2%) |
28 (68.3%)
13 (31.7%) |
259 (63.3%)
150 (36.7%) |
0.487 |
| Insulin use
Yes
No |
6 (1.6%)
362 (98.4%) |
10 (24.4%)
31 (75.6%) |
16 (3.9%)
393 (96%) |
<0.001 |
| Alive at last follow up
Yes
No |
223 (60.6%)
145 (39.4%) |
34 (82.9%)
7 (17.1%) |
257 (62.8%)
152 (37.2%) |
0.005 |
