Variable Reference P-value HR (95%CI)
No Metformin Metformin 0.009 3.08 (1.32-7.19)
Age   0.004 1.03 (1.01-1.05)
Gender: Female Male 0.665 1.08  (0.77-1.50)
Race: Other White 0.529 1.21 (0.67-2.2)
Diabetes: No Diabetes 0.293 0.78 (0.48-1.25)
Smoking: Current Smoking: Previous 0.58 1.13 (0.79-1.62)
Smoking: Never Histology: AdenoCa Histology: Other Path stage: IA Insulin: No use Smoking: Previous Histology: SqCC Histology: SqCC Path stage: IB Insulin: Use 0.028 0.036 0.158 0.224 0.918 0.44 (0.21-0.92) 0.68 (0.48-0.98) 0.64 (0.35-1.19) 0.81 (0.58-1.14) 1.05 (0.393-2.82)
Table 2: Factors associated with overall survival in multivariate model. Higher hazard ratio (HR) denotes increased risk of death. SqCC: Squamous cell cancer, AdenoCa: Adenocarcinoma.