Variable
Reference
P-value
HR (95%CI)
No Metformin
Metformin
0.009
3.08 (1.32-7.19)
Age
0.004
1.03 (1.01-1.05)
Gender: Female
Male
0.665
1.08 (0.77-1.50)
Race: Other
White
0.529
1.21 (0.67-2.2)
Diabetes: No
Diabetes
0.293
0.78 (0.48-1.25)
Smoking: Current
Smoking: Previous
0.58
1.13 (0.79-1.62)
Smoking: Never
Histology: AdenoCa
Histology: Other
Path stage: IA
Insulin: No use
Smoking: Previous Histology: SqCC Histology: SqCC Path stage: IB Insulin: Use
0.028 0.036 0.158 0.224 0.918
0.44 (0.21-0.92) 0.68 (0.48-0.98) 0.64 (0.35-1.19) 0.81 (0.58-1.14) 1.05 (0.393-2.82)
Table 2:
Factors associated with overall survival in multivariate model. Higher hazard ratio (HR) denotes increased risk of death. SqCC: Squamous cell cancer, AdenoCa: Adenocarcinoma.