| Parameters |
Univariate analysis |
Multivariate analysis |
| HR |
95% CI |
p-value |
HR |
95% CI |
p-value |
| Age, years ≤60 vs >60 |
3.84 |
2.06-22.7 |
0.001 |
0.46 |
0.09-2.17 |
0.32 |
| Type of first line-chemotherapy Single agent vs combination Antracyclines vs Taxanes vs other |
1.39 0.85 |
0.57-3.43 0.39-6.71 |
0.4 0.93 |
- |
|
|
| Ki-67 ≤ 20% vs >20% |
2.21 |
1.37-6.51 |
0.0009 |
2.37 |
1.11-5.07 |
0.02 |
| Necrosis negative vs positive |
0.70 |
0.2-2.07 |
0.47 |
- |
|
|
| Lympho-vascular invasion negative vs positive |
0.42 |
0.12-0.97 |
0.04 |
1.19 |
0.31-4.55 |
0.79 |
| Visceral disease yes vs not |
0.17 |
0.11-0.69 |
0.006 |
3.84 |
0.7-21.15 |
0.12 |
| e-cadherin negative vs positive |
0.50 |
0.20-1.38 |
0.19 |
- |
|
|
| Aldh1 negative vs positive |
0.77 |
0.29-1.93 |
0.55 |
- |
|
|
| CK5 or CK 17 negative vs positive |
0.57 |
0.19-1.44 |
0.21 |
- |
|
|
| AR negative vs positive |
2.88 |
1.32-9.43 |
0.01 |
2.21 |
0.98-2.55 |
0.05 |
