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Table 3b: Cytotoxicity of PTX on NCI-H460 cells (Dose fixation study). PTX was incubated with cells for 24 h and % cytotoxicity was observed by MTT assay. Cell death was observed in a concentration (0–10 μg/mL) dependent manner in NCI-H460 cells. 5 μg/mL PTX showed 50% cell death (IC50) in NCI-H460 cells. IC50 values are indicated as the mean ± S.D. of three independent experiments performed. (S.D= standard deviation). |