Psammaplin A or MG132 Concentration(μL)
Treatment Psammaplin A 1 μM CPT no CPT
Treatment MG132 MG132 1 μM CPT no CPT
NCI-H226 BAP1 null cells (#cells per field ofview)
0
80 240
250 300
1/10 000
15 150
200 250
1/1000
15 10
112 65
1/500
50 200
5 7
SKN cells (# cells per field of view)
0
800 000 900 000
10 000 200
1/10 000
800 000 900 000
200 150
1/1000
800 000 900 000
800 000 80
1/500
600 000 800 000
800 000 500 000
Source : Jamile Charkie, Cross-Cancer Institute
Table 1:
Two cell lines were tested with varying concentrations of Psammaplin A or MG132, in combination with 1 μM CPT or no CPT.