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Figure 1: miR-203 is associated with long-term survival of ovarian cancer patients and is downregulated in ovarian serous carcinoma. A. miR-203 expression in the top and lower 10% surviving patients with ovarian cancer was analyzed from the TCGA database. Significant differences was analyzed using Student’s T test. * p = 0.017). B. miR-203 is downregulated in ovarian serous carcinoma compared to normal control ovaries (p = 0.034). C. miR-203 expression in SKOV3 and OVCAR3 cells transduced with miR-203 lentiviral and EGFP control vectors was determined by polyA tailing real-time RT-PCR and normalized to expression of the non-coding RNA U6. |