Figure 3: Comparative expression analysis of miR-21 and miR-146b in 18 paired samples of FFPE cell blocks of tumor and normal tissue from papillary thyroid carcinoma (PTC) patients’ individually using qRT-PCR. Combined data for both races (A and C) and race-specific data (B and D) is presented. There was a significant up-regulation of miRNA-21 in African American (AA) patients when compared to Caucasian American (CA) patients (3B). Overall, while miR-146b appears to be upregulated, a larger percentage of CA samples than AA samples followed this trend (3D). The miRNAs expression was normalized using RNU48 miRNA. P values represent comparison between normal and tumor (3A, 3C), and CA tumor vs AA tumor (3B, 3D) using F test.