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Figure 5: Comparative expression analysis of miR-31 and miR-3613 in 22 paired samples of FFPE cell blocks of tumor and normal tissue in PTC patients’ individually using qRT-PCR. Combined data for both races (A and C) and race-specific data (B and D) is presented. In combined data for miR-31, there appears to be no trend regarding differential miRNA expression (5A). When individual races were examined, miR-31 was mostly up-regulated in CA patients and primarily down-regulated in AA patients (5B). No such race-specific difference was observed in miR-3613. The miRNAs expression was normalized using RNU48 miRNA. P values represent comparison between normal and tumor (5A, 5C), and CA tumor vs AA tumor (5B, 5C) using F test. |