Study Year Number of treatment related complications (percent) Type of complication, number of each
Kilburn 2014 4(9%) 1 brainstem necrosis, 1 disequilibrium, 1 hemiparesis, 1 facial numbness with hemiparesis
Peterson 2014 1(2%) 1 fatal brain hemorrhage
Jung 2013 0  
Sengoz 2013 2 (4%) 2 asymptomatic peritumoral image changes
Kawabe 2012 7 (4%) 7 peritumoral edema (1 severe)
Leeman 2012 3 (8%) 1 nausea, 2 headache
LI 2012 1 (4%) 1 peritumoral edema
Lin 2012 2 (4%) 1 radionecrosis, 1 facial palsy
Yoo 2011 1 (3%) 1 pontine hemorrhage
Valery 2011 4 (13%) 4 headache controlled with corticosteroids
Hatiboglu 2011 12 (20%) 4 hemiparesis, 2 cranial nerve deficits, 3 headache, 4 nausea/vomiting, 2 peritumoral hemorrhage
Kelly 2011 2 (8%) 1 ataxia, 1 confusion
Koyfman 2010 5 (12%) 2 radionecrosis, 1 weakness, 1 ataxia, 1 pin-site bleed
Samblas 2009 0
Lorenzoni 2009 0  
Kased 2008 4 (10%) 2 radionecrosis, 1 hemiparesis, 1 pontine hemorrhage
Hussain 2007 1 (5%) 1 hemiparesis
Fuentes 2006 0
Yen 2006 0  
Shuto 2003 2 (8%) 2 peritumoral edema
Huang 1999 7 (27%) 4 nausea/vomiting, 3 seizures
Table 5: Treatment associated complications [1,2,4-22].