Groups Group I Group II Group III Group IV Group V TC(mg/dl) 8.23 ± 0.8 8.55 ± 0.18 a, ns 18.22 ± 0.08 a,*** 14.35 ± 0.14 b,* 9.32 ± 0.34 b,*** HDL-c(mg/g wet tissue) 41.65 ± 1.07 45.24 ± 0.52 a, ns 22.95 ± 0.45 a,*** 30.08 ± 0.80 b,* 42.38 ± 0.06 b,*** LDL-c(mg/g wet tissue) 54.33 ± 0.44 60.50 ± 0.41 a, ns 132.28 ± 0.15 a,*** 104.41 ± 0.62 b,* 69.40 ± 0.02 b,*** VLDL-c(mg/g wet tissue) 18.32 ± 0.15 19.05 ± 0.32 a, ns 53.20 ± 1.90 a,*** 40.12 ± 0.14 b,** 21.12 ± 0.05 b,*** TG 93.40 ± 1.56 94.88 ± 1.01 a, ns 192.32 ± 1.57 a,*** 156.71 ± 1.20 b,* 121.67 ± 1.34 b,***

Values are expressed as mean ± SEM for Six animals. Group I: Normal control; Group II: PH-control; Group III: NDEA; Group IV: NDEA+SIB(25mg/kg/day); Group V: NDEA+SIB(50mg/kg/day). Comparisons: a = groups II and III with group I; b = group IV and V with group III. Significant: nsp>0.05; *p<0.05; **p<0.01; ***p<0.001.

Table 1: Effect of Silibinin (SIB) on lipoprotein levels in plasma of induced and treatment groups.