Figure 4: Vessel dilator at 10 μM inhibits 98% of the phosphorylation of mitogen- activated protein kinase kinase (MEK 1/2), ,which was maximal at two hours and significant at p<0.00001 when evaluated by analysis of variance (ANOVA). MEK 1/2 is at 45 kDa while B-actin(loading control) is 42 kDa. The relative intensity in the bar graphs is a comparison against untreated MEK 1/2 (100% intensity). Reprinted with permission from Anticancer Res. 27:1387-1392, 2007.