Figure 1: Prostate adenocarcinoma Gleason pattern 3. A. Negative immunoreactivity for CD10. Positive marker the normal prostate glands (x 200). B. Strong membranous and apical cytoplasmic IHC staining for CD10 (x 200). C. The same area as in B. Negative immunoreactivity for ET-1. Positive marker the capillary endothelium (arrows) (x 200). D. The same area as in A. Strong cytoplasmic IHC staining for ET-1 (x 200).