Cells Treatment α (Gy-1) control β (Gy-2) control α -enhanc. factor β -enhanc. factor
SWp sham 0.10 ± 0.03 0.055 ± 0.008    
  10nM gemcitabine 0.30 ± 0.06* 0.053 ± 0.007 3.0 0.96
SWg sham 0.09 ± 0.02 0.040 ± 0.006    
  100µM gemcitabine 0.09 ± 0.03 0.090 ± 0.041† 1.0 2.25
A2780 sham 0.80 ± 0.10 na    
  10nM gemcitabine 1.10 ± 0.15* na 1.4  
AG6000 sham 0.83 ± 0.13 na    
  50µM gemcitabine 1.11 ± 0.20† na 1.3  
Significant difference with *P<0.01, †P<0.05, na is not applicable
Table 2: Values of the linear-quadratic parameters a and and enhancement factors from cells treated with ionizing radiation only and gemcitabine-sensitized radiation dose survival curves of gemcitabine-sensitive (SWp and A2780) and gemcitabine-resistant (SWg and AG6000) cells.