Figure 4: (A) Chemical structure of kanamycin. (B) Dark black columns represent the binding energies of kanamycin with different riboswitches, dark grey columns show the binding energy of each riboswitch with its own natural ligands and light grey columns show the binding energy of each riboswitch with ampicillin based on AutoDock Vina results. (C) The interaction between the riboswitches and kanamycin. Hydrogen bindings are demonstrated with green dot lines.