Acanthosis nigricans is a skin condition characterized by areas of dark, velvety discoloration in body folds and creases. The affected skin can become thickened. Most often, acanthosis nigricans affects your armpits, groin and neck.
Acanthosis nigricans is seen in both men and women and most commonly seen in those who are overweight or have diabetes or perdiabetic condition. Acanthosis nigricans skin patches occur when epidermal skin cells begin to reproduce rapidly. This abnormal skin cell growth is most commonly triggered by high levels of insulin in the blood.
Disease statistics: In Australia the prevalence rate of Acanthosis Nigerians was found to be present in 19.4% of 1730 patients, including all age ranges studied. Acanthosis Nigerians was most prevalent among persons with more diabetes risk factors. Patients with Acanthosis Nigerians were twice as likely as those without Acanthosis Nigerians to have type 2 diabetes (35.4% vs. 17.6%).