alexa Bleeding Disorders | Australia | PDF | PPT| Case Reports | Symptoms | Treatment

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Bleeding Disorders

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  • Bleeding Disorders

    Bleedind disorder is a set of disorders, or disease which normally affect the process of clotting of our blood. This bleeding can be in many cases like during an accident, trauma condition, surgery, injury or a menstrual cycle. These bleeding disorders are not only associated with bloods leaving out from our body, rather it can also be an internal bleeding beneath our skin or brain. These may be hemophilia A and B or Willebrand’s disease for example. Sometimes this disease is also termed as royal disease.
  • Bleeding Disorders

    The main symptom of bleeding disorder would be excessive bleeding and prolonged clotting time during normal injuries also. These can also easily identified by frequent nose bleeding, heavy menstrual bleeding and unexplained bruishing.
  • Bleeding Disorders

    There are mainly two common type of instant treatment available for bleeding disorder, which is iron supplementation or clotting factor repalacement and blood transfusion. These are the therapeutic aspect, but extended research is in progress in various countries, where this disease has a greater prevalence rate.
  • Bleeding Disorders

    In Australia prior to 1992, many patients with bleeding disorders were exposed to hepatitis C through blood products. However, the incidence, complications and response to treatment of chronic hepatitis C (CHC) in this population are poorly characterized. The aim of this study was to examine the prevalence of CHC and response to treatment in an Australian bleeding disorders population. Demographic data, virological data and liver disease status from these 700 patients with inherited bleeding disorders were analysed. Of these 700 patients, 424 (61%) had been tested for CHC infection and 219 (52%) were hepatitis C antibody positive, with the prevalence approaching 100% in patients with severe bleeding disorders. Of 219 patients, 73 (33%) had received treatment for their infection with a response rate of 33/73 (45%) across all genotypes. Of 219 patients, 34 (16%) had spontaneous viral clearance. When measured with transient elastography, 44/98 (45%) patients with CHC had significant liver fibrosis and 15/98 (15%) had liver cirrhosis. Of 130 patients, 38 (29%) with CHC infection had no evidence of follow-up with an appropriate clinician in the past 2 years.

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