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Desmoid Tumour

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  • desmoid tumour

    Pathophysiology: Desmoid tumors are cytologically bland fibrous neoplasms originating from the musculoaponeurotic structures throughout the body. They often appear as infiltrative, usually well-differentiated, firm overgrowths of fibrous tissue, and they are locally aggressive. They commonly arise from the rectus abdominis muscle in postpartum women and in scars due to abdominal surgery, they may arise in any skeletal muscle.

  • desmoid tumour

    Treatment: A biopsy is necessary to diagnose a desmoid tumor. If diagnosed patients should be evaluated by a multi-disciplinary team of surgeons, medical oncologists, radiation oncologists, geneticists and nurses. There is no cure for desmoid tumors and when possible patients are encouraged to enlist in clinical trials. A biopsy is always indicated as the definitive method to determine nature of the tumour.

  • desmoid tumour

    Statistics: Desmoid tumours are a group of rare soft tissue tumours of mesenchymal origin, which arise following the monoclonal proliferation of well-differentiated fibroblasts. There are an estimated 2 to 4 cases per million people per year. They represent 0.03% of all tumours and less than 3% of all soft tissue tumours.

  • desmoid tumour

    Major Research: It is aimed to illustrate the pre- and post-treatment imaging findings of musculoskeletal desmoidtumours and describe current treatment methods. Imaging of histologically proven cases of desmoid tumours at St. Vincent's Hospital, Melbourne, were obtained via picture archiving communication system (PACS) and then assessed by two musculoskeletal radiologists.

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