Splenomegaly means enlargement of the spleen Cirrhosis of the liver, Glandular fever, Haemolytic anaemias, Cystic fibrosis, Cytomegalovirus, etc.
The sensitivity for detection of ultrasound-documented splenic enlargement is 60 to 70% for palpation and 60 to 80% for percussion. Up to 3% of normal, thin, people have a palpable spleen.
Treatment for splenomegaly depends on the underlying condition. For example, radiation therapy and chemotherapy may be used to treat cancers, while regular blood transfusions are needed to manage thalassaemia. Other helpful signs include a splenic friction rub that suggests splenic infarction and epigastric and splenic bruits that suggest congestive splenomegaly.
Generalized adenopathy may suggest a myeloproliferative, lymphoproliferative, infectious, or autoimmune disorder.