alexa Gilberts Syndrome | Australia| PDF | PPT| Case Reports | Symptoms | Treatment

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Gilberts Syndrome

  • Gilberts Syndrome

    Introduction

    Gilbert's syndrome is a common harmless mild disorder in which the liver is unable to properly process the yellowish-brown pigment called bilirubin. Gilbert's syndrome typically does not need treatment, but may affect the toxicity of certain medication. The medical name for this is ‘unconjugated hyperbilirubinemia’.

  • Gilberts Syndrome

    Symptoms

    In GS the mutation causes ‘reduced gene expression’, meaning that it limits production of thespecific UGT enzyme (called UGT1A1) responsible for conjugating bilirubin . Symptoms Tiredness, Mild weakness, Mild tummy (abdominal) pains and mild feeling of sickness (nausea).

  • Gilberts Syndrome

    Statistics

    Gilbert's Syndrome causes significant morbidity and mortality worldwide. The incidence and Prevalence of this disease is varying among different populations. It is reported that, in Australia, Gilberts Syndrome affects 3-7% of the total population. This disease mainly affects the age group of 20-30 years.

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