alexa Movement disorders | Australia | PDF | PPT| Case Reports | Symptoms | Treatment

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Movement Disorders

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  • Movement disorders

    Patho Physiology:
    Movement disorders are neurological conditions that affect the speed, fluency, quality, and ease of movement. Abnormal fluency or speed of movement (called dyskinesia) may involve excessive or involuntary movement (hyperkinesia) or slowed or absent voluntary movement (hypokinesia). Electromyography (EMG) is a diagnostic procedure to assess the health of muscles and the nerve cells that control them (motor neurons).

  • Movement disorders

    Statistics:
    The prevalence of all common categories of movement disorders was 28·0% (95% CI 25·9–30·1). Proportions in men (27·6% [95% CI 24·5–30·7]) and women (28·3% [25·5–31·2]) were closely similar and sharply increased with age (from 18·5% [15·0–22·0] in 50–59-year olds to 51·3% [44·9–57·7] in 80–89-year olds). Almost half of all patients (90/214) had moderate-to-severe disease expression, but only 7·0% (15/214) received standard drug treatment. 

  • Movement disorders

    Treatment:
    Caffeine and stress should be avoided, and good sleep is recommended.the first medication choices are beta blockers such as propranolol or alternately, nadolol and timolol. Atenolol and pindolol are not effective for tremor.[1] The anti-epileptic primidone is also effective for movement disorders.Second-line medications are the anti-epileptics topiramate, gabapentin and levetiracetam, or benzodiazepines like alprazolam.

  • Movement disorders

    Major Research:
    Harmaline is a widely used model of essential tremor (ET) in rodents. Harmaline is thought to act primarily on neurons in the inferior olive (IO). Olivocerebellar neurons exhibit rhythmic excitatory action when harmaline is applied locally.

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