alexa Alexandra Lucas
ISSN: 2155-9880

Journal of Clinical & Experimental Cardiology
Open Access

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Alexandra Lucas

University of Florida USA

Dr. Lucas moved to the University of Florida in 2006 from Canada where she trained at McGill University and the Universities of Alberta and Western Ontario. Dr. Lucas moved from the John P. Robarts Research Institute and University of Western Ontario in London, ON, Canada, where she has been a professor and principal investigator studying inflammation in vascular disease. More recently, Dr. Lucas’s research group has examined the roles of serineprotease inhibitors (serpins) as well as the glyocalyx and chemokines in transplant vasculopathy. This work has led to studies on the roles of serpins and glycosaminoglycans both as mediators and as potential therapeutic targets in transplant rejection as well as in acute inflammatory viral hemorrhagic fevers and aggressive pancreatic cancer. Dr. Lucas is a co-inventor and co-founding scientist for Viron Therapeutics, Inc., a biotechnology company that has now successfully completed a clinical trial analyzing a viral anti-inflammatory serpin, a purified protein therapeutic, as a new class of therapeutic agent, holding 17 patents.  Dr. Lucas is a practicing interventional cardiologist in addition to running an active basic research lab in vascular inflammatory research. She has over 127 papers and reviews and 18 patents published as well as two new patents in preparation for submission by the University of Florida. Dr. Lucas has held AHA and NIH funding. Dr. Lucas has been an active member of the Canadian Society for Atherosclerosis and Thrombosis Board having also served as Editor-in-Chief for two journals. She additionally serves on an American Heart Association grant panel as well as reviewing for the NIH.  Dr. Lucas has recently been an invited plenary speaker, presenting research from her lab on serpins and the glycocalyx in inflammatory vascular disease and viral sepsis. She is additionally on the editorial board for several journals.  Dr. Lucas also practices karate and is a co-director for an annual medical mission to Fte. Liberté in Haiti.

Research Interest

Coronary artery disease, Angina, Internal medicine, Cardiovascular risk


The Serpintine Solution

Alexandra Lucas, MD, FRCP(C)*, Sriram Ambadapadi, PhD, Brian Mahon, PhD, Kasinath Viswanathan, PhD, Hao Chen, MD, PhD, Liying Liu, MD, Erbin Dai, MD, Ganesh Munuswami-Ramanujam, PhD, Jacek M. Kwiecien, DVM, MSc, PhD, Jordan R Yaron, PhD, Purushottam Shivaji Narute, BVSc & AH, MVSc, PhD, Robert McKenna, PhD, Shahar Keinan, PhD, Westley Reeves, MD, PhD, Mark Brantly, MD, PhD, Carl Pepine, MD, FACC and Grant McFadden, PhD

Editorial: J Clin Exp Cardiolog 2017, 8: e150

DOI: 10.4172/2155-9880.1000e150

The Heart of Haiti: A Pure Soul from Tortured Soil

Alexandra Lucas*, Gail Ellison, Seana McFadden, Jen Lucas, Baron McFadden, Grant McFadden, Daniel Bachmann, Howie Werman, Diane Gorgas, Lynn Morrison, Christian Dekowny, Lee Platt, Jeri Platt and Marsha Bryant

Editorial: J Clin Exp Cardiolog 2016, 7: e144

DOI: 10.4172/2155-9880.1000e144

Glycosaminoglycans (GAGs) in Cardiovascular Disease: Searching for the Sweet Spot

Alexandra Lucas*, Dara Wakefield, Marsha Bryant, Hao Chen, Sriram Ambadapadi, Sufi M Morshed, Desyree DeJesus, William Clapp and Grant McFadden

Editorial: J Clin Exp Cardiolog 2016, 7: e141

DOI: 10.4172/2155-9880.1000e141

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