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The principal research interests of Dr. Brunicardi are in the areas of pancreatic physiology, differentiation and pancreatic cancer. Dr. Brunicardi is a renowned gastrointestinal surgeon-scientist who was a member of the CURE: DDRC from 1989 to 1995, when he was recruited to Baylor College of Medicine in Houston, Texas as George Jordan Professor and Chief of General Surgery. In 1999, he became DeBakey/Bard Professor and Chairman of the Michael E. DeBakey Department of Surgery at Baylor and held that leadership position for 12 years. In 2011, Dr. Brunicardi rejoined the UCLA faculty as Professor and Chief of the Santa Monica-UCLA General Surgery Group and a Vice Chair of the Department of Surgery for Surgical Services at Santa Monica-UCLA Medical Center. At the same time, Dr. Brunicardi also rejoined the CURE: DDRC where his laboratory will be located. His clinical expertise includes gastrointestinal surgery and surgery of neuroendocrine tumors, and his research focuses on translational genomic medicine and surgery. Recently, he has advanced the notion that the transcription factor PDX-1 which plays a key role in determining cell lineages in the pancreas also plays a pro-oncogenic role in the development of pancreatic cancer.
Pancreatic islets cell physiology and transplantation.