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The theme of Dr. Christofidou-Solomidou's research is pulmonary inflammation and cell adhesion molecule regulation/expression. Projects involve the development of oxidant-induced acute and chronic lung injury animal models for the study of diseases such as ARDS, sepsis, radiation induced pneumonitis/fibrosis, and oxygen toxicity. Specific projects focus on the development of antioxidant methodologies such as immune conjugates for the targeting of anti-oxidant enzymes such as Catalase and Superoxide Dismutase to the pulmonary endothelium using antibodies to endothelial antigens. Recent work extends to the use of dietary alternative antioxidant agents such as curcumin, flaxseed or phenolic compounds in ameliorating acute and chronic oxidative lung disease.
Emergency Medicine, Oncology, Respiratory Medicine, Pulmonology, Space Science
Berman Abigail T, Turowski Jason, Mick Rosemarie, Cengel Keith, Farnese Nicole, Basel-Brown Lisa, Mesaros Clementina, Blair Ian, Lawson James, Christofidou-Solomidou Melpo, Lee James and Rengan Ramesh
Research Article: J Pulm Respir Med 2013, 3: 154
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