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Yang Dan's laboratory studies how visual information is processed by cortical circuits and how circuit dynamics vary across brain states. Using both bottom-up and top-down approaches and a combination of electrophysiology, imaging, and computational techniques, her group aims to understand neural processing at multiple levels, from single synapses to cortical microcircuitry, and from network dynamics to animal behavior.
Research aims to elucidate (1) what circuits in the mammalian brain control sleep, and (2) mechanisms by which the frontal cortex exerts top-down executive control. We use a variety of techniques, including optogenetics, electrophysiology, imaging, and virus-mediated circuit tracing.
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