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Silvia Di Loreto of Italian National Research Council, Rome with expertise in Neuroscience at Institute of Translational Pharmacology, National Council of Research, Italy
Study of the molecular and genetic mechanisms underlying the processes of immunogenetics and neurodegenerative and neoplastic etiology. In particular: a) determination and characterization of potential biochemical markers and clinical indices of monitoring in 'onset and evolution of neuro / diseases of the immune b) study of the role of molecules of the immune processes of neurodegeneration and aging; c) identification of possible correlations between gene polymorphisms and cognitive disorders and / or neurological disease; d) occurs at the clinical level of the role of genetic polymorphisms (HLA, MICA, KIR, HLA-G, cytokines) in the onset / prevention of complications after transplant, in susceptibility to autoimmune diseases, cancer and allergies; e) comparing the allele and genotype frequencies MICA, TNF-alpha and HLA-G in North Africa with the European and analyze potential associations loci MICA, TNF-a in autoimmune diseases.
Case Report: Hereditary Genet 2014, 3: 138