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The Varani research group studies the interactions between proteins and nucleic acids to understand how proteins bind nucleic acids at the physical chemical level, with the aim of being able to rationally design new peptides and small molecule drugs that are able to control human regulatory networks or repress viral replication. Members of the group use spectroscopic (NMR), crystallographic, computational and biochemical techniques to achieve this goal.
Garry W. Buchko, Isabelle Phan, Lisabeth Cron, Robin Stacy, Lance J. Stewart, Bart L. Staker, Thomas E. Edwards, Gabriele Varani, Wesley Van Voorhis and Peter J. Myler
Editorial: Metabolomics 2013, 3:e124