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Gareth Jones | OMICS International
ISSN: 2161-105X

Journal of Pulmonary & Respiratory Medicine
Open Access

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Gareth Jones

 Drug Safety Research and Development,  Pfizer Research Laboratories, UK


 Dr. Gareth obtained his PhD under the supervision of Dr. Colin Berry (School of Biosciences, Cardiff University) where he studied bacterial toxins active against mosquitos, which are vectors for many human viruses and parasites. Here he gained invaluable experience in biochemical and molecular biology techniques, and discovered novel toxins that display activity against problematic mosquito populations that have developed resistance against mosquitocidal toxins used currently in the field.

To fulfil his desire of linking research more directly with human disease, in 2006 he joined the laboratory of Prof. Simon Jones (School of Medicine, Cardiff University). Here he acquired an interest in understanding how cytokines govern the adaptive immune response during chronic inflammation. He made discoveries relating to how inflammatory cytokines, central to arthritis progression, differentially regulate naïve and effector T-helper cell populations. These include identifying a novel role for IL-6 trans-signalling in supporting TH-17 cell responses, and characterising the cytokine TL1A (TNFSF15) as an inhibitor of TH-17 cell differentiation.

Research Interest

 Pulmonary Lymphoma, Pulmonary Eosinophilia, Respiratory Syncytial Virus Infection (RSV),Cytokine inflammation