Journal of Data Mining in Genomics & Proteomics

George Nemer

Biography

      Dr. George Nemer earned his B.Sc degree in Biology from the American University of Beirut (1992). He received his Ph.D. degree with high distinction (the thesis being classified in the upper 5% in its field) in Molecular Pharmacology from the Université de Montréal (2001). Dr Nemer worked as a research fellow at the Clinical Research Institute of Montreal (IRCM) before moving to the department of Biochemistry in the Faculty of Medecine at AUB (October 2002). He received many scholarships from Pfizer Canada and Gibco-Ingelheimer for his work on transcription factors in heart development and diseases, which were published in prestigious journals including Cell, which high-lightened the impact of his published article on the role of Tbx5 in the Holt-Oram syndrome by using one of its figures as a cover page for its September 21, 2001 issue. Since moving to AUB, Dr Nemer is focusing on the genetic and molecular bases of congenital heart diseases (CHD) in the Lebanese population. CHDs occur in 1 per 100 live births, and are still the major risk factors for early morbidity in neonate children. In collaboration with Dr Fadi Bitar who established the first Cardiac Registry Center at the AUH with more than 1000 patients, Dr Nemer is exploring the genetic causes of these CHDs. Mutations if found will be analyzed in vitro, and in vivo mice models will be generated to understand the molecular bases behind such defects. Computational analysis of the mutated proteins will help design novel drugs and trials can be started on those mice models.

Research Interest

Data analysis Genomics