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Hiroshi Ohrui received Ph.D. in 1971 from The University of Tokyo. He joined RIKEN in 1966 as a researcher. In 1981, he moved to Tohoku University as an Associate Professor and promoted to Full Professor in 1997. In 2006, he moved to Yokohama College of Pharmacy as Professor. He has received several awards including The Japan Society for Analytical Chemistry Award (2004) and the Japan Academy Prize (2010).
Organic synthesis, chiral discrimination, and medicinal chemistry
Development of 2′-Deoxy-4′-C-Ethynyl-2-Fluoroadenosine (EFdA) which has Supremely High Anti-HIV Activity and Low Toxicity and Prevents the Emergence of Resistant HIV Mutants, and Discovery of Different Substrate Selectivity between Viral and Human Nucleic Acid Polymerases
Review Article: J Antivir Antiretrovir 2013, S10: 002