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His is working on advance knowledge on the pathophysiology of acute pulmonary thromboembolism, specifically on the understanding of its mechanisms for hypoxemia and pulmonary hypertension. After acute pulmonary embolism, e.g. after a long flight or recovering from surgery, patients often suffer from lack of oxygen and low blood pressure that can be life threatening. Through research, we now understand that underlying problems are related to the abnormal distribution of blood flow in the lung caused by the obstructing blood clots, resulting in its heterogeneous matching to the oxygen supply through the airway and the failure of the heart to pump blood through the blocked and constricting pulmonary vessels.
Pulmonary circulation, pulmonary embolism, Gas exchange, Regional blood flow, Fluorescent microspheres
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