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Laura Manna Dipartimento di Scienze Cliniche Veterinarie, Italy works on the Development and Clinical Trial of a Novel DNA Vaccine as Immunotherapy. This study on as aimed to evaluate the effect of a DNA vaccine based on two Leishmania antigens in leishmaniotic dogs. Twelve leishmaniotic dogs from a Leishmaniasis-endemic area (Naples, Italy) received three consecutive injections of DNA vaccine at 15-days intervals.
Visceral leishmaniasis (VL) is a life-threatening disease of medical, social and economic importance in endemic areas. Dogs are the main reservoir of Leishmaniainfantum. In this study, the authors investigated a group of 56 natural infected dogs to establish the relationship between parasite load and various clinical forms of leishmaniasis
Laura Manna, Ilaria Michela Piras, Valentina Cipri, Alberto Alberti, Italia Della Peruta, Carlo Maria Del Pizzo, Nicoletta Gammarano, Elisabetta Coradduzza, Carla Cacciotto, Marco Pittau, Angelo Elio Gravino and Bernardo Chessa
Research Article: J Vaccines Vaccin 2012