alexa Leonard Amaral
ISSN: 2167-7956

Journal of Biomolecular Research & Therapeutics
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Leonard Amaral

Leonard Amaral Emeritus Professor Institute of Hygiene & Tropical Medicine of Lisbon Universidade Nova de Lisboa Hungary
Biography

Leonard Amaral, M.D., Ph.D., Emeritus Professor, Institute of Hygiene & Tropical Medicine of Lisbon; Universidade Nova de Lisboa; Travel Medicine of the Centro de Malaria e Doenças Tropicais of the Institute of Hygiene and Tropical Medicine (CMDT), Lisbon, Portugal. and Distinguished Invited Scientist Fellow of the Fundacao de Ciencias e Tecnologia de Portugal Invited Professor, Institute of Medical Mycrobiology and Medical Immunology, University of Szeged, Szeged, Hungary.

Research Interest

Development of therapy by which the resistance of MDR/XDR Mtb is by-passed and the non-killing macrophage is transformed into a killer of MDR/XDR Mtb. Therapy of MDR/XDR TB with an inexpensive drug that is beyond patent protection, has no serious toxicity and has been now shown to cure XDR TB. Development of new methods for the characterisation, evaluation and assessment of efflux pumps that render bacteria and cancer cells resistant to therapy. Demonstration of biophysical/biochem mechanisms by which efflux pumps render bacteria multi-drug resistant. Development of new theories for therapy of cancer based upon the 2nd law of thermodynamics. Development of a new chemistry system based upon the use of lasers for modification of bioactive compounds.

Publications

Synergism between Antiplasmid Promethazine and Antibiotics In Vitro and InVivo

Joseph Molnár, Yvette Mándi, Gabriella Spengler, Leonard Amaral1,Ibolya Haszon, Sándor Turi and Miklós Kásler

Research Article: Mol Biol 2015, 4: 119

Advances in Personalised Treatment of Multi-drug Resistant Tuberculosis

Leonard Amaral and Dick van Soolingen

Commentary: Biochem Pharmacol (Los Angel) 2014, 3: 148

Synergism between Antiplasmid Promethazine and Antibiotics In Vitro and In Vivo

Joseph Molnár, Yvette Mándi, Gabriella Spengler, Ibolya Haszon, Sándor Turi, Miklós Kásler, and Leonard Amaral

Review Article: Biochem Pharmacol 2014, 3: 139

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